New crown super mutation virus attacks Israel, the biggest short board is this crowd! China should also be vigilant

要点：

Key points:

以色列原计划从7月1日起正式开门，允许来自低风险国家的个人游客出行。但突然间，新型冠状病毒肺炎证实人数急剧上升，计划不得不推迟1个月。

Israel originally planned to officially open its door from July 1, allowing individual tourists from low-risk countries to travel. But suddenly the novel coronavirus pneumonia confirmed a sharp rise in the number of people, and the plan had to be postponed for 1 months.

乔维德-19又是怎么潜入以色列的？

How did COVID-19 sneak into Israel again?

这和攻击性的delta变异病毒有关吗？

Does it have anything to do with the aggressive delta mutant virus?

我们先来听听当地一位媒体居民的经历。

Let's first listen to the experience of a local media resident.

这一波疫情从6月21日开始，以色列当天报告了123例新病例，这是两个多月来首次单日报告100多例新病例。

This wave of epidemic began on June 21, and Israel reported 123 new cases on that day, which is the first time in more than two months that more than 100 new cases were reported on a single day.

这只是个开始。

This is just the beginning.

6月24日，新增病例227例，创今年4月7日以来单日最大增幅。首都特拉维夫以北的一个小镇，隔离了数千人。

On June 24, 227 new cases were added, which was the largest increase in a single day since April 7 this year. A small town north of Tel Aviv, the capital, has isolated thousands of people.

贝内特说，这波疫情可能是由"三角洲"变异病毒引起的，主要来自以色列的海外回国他建议说："如果没有必要，就不要出国。"。

Bennett said that this wave of epidemic may be caused by the "delta" mutant virus, mainly from the overseas return of Israel. "Do not go abroad if it is not necessary," he advised.

以色列卫生部强调，由于受到传染性极强的"三角洲"病毒的威胁，原本暂停的"室内强制佩戴口罩"制度立即重启，口罩应在室外佩戴。

Israel's Ministry of health stressed that due to the threat of highly infectious "delta" virus, the originally suspended system of "mandatory wearing masks indoors" was immediately restarted, and masks should be worn outdoors.

卫生部长尼桑·霍洛维茨也不情愿地祝愿公众"玩得开心"，但"我们必须按照指示戴口罩，最重要的是健康"。

Health minister Nizan Horowitz also reluctantly wished the public "have a good time", but "we must wear masks according to the instructions, and the most important thing is health".

总之，以色列的疫情确实得到了很好的控制。从4月中旬开始，就出现了零诊断（是的，我们认为传统的零诊断对其他人来说是个神话

In a word, the epidemic situation in Israel is really well controlled. Since the middle of April, there has been a zero diagnosis（ Yes, we think the conventional zero diagnosis is a myth to others

以色列在疫苗接种方面也做得很好。据统计，在完成两剂疫苗接种的人群中，约有60%的人在过去6个月处于世界最高水平。除自然感染率10%外，以色列在一定程度上实现了大规模免疫接种。

Israel has also done a good job of vaccination. According to statistics, about 60% of the people who have completed the two doses of vaccination have been at the highest level in the world in the past six months. In addition to the natural infection rate of 10%, Israel has achieved mass immunization to a certain extent.

主要感染人群为学生，该人群接种率不高。

The main infected people are students, and the vaccination rate of this group is not high.

以色列已开始弥补其不足，并开始大规模为青少年接种疫苗。6月24日，11000人接种了疫苗，其中近8000人是12-15岁的儿童（第一次接种）。

Israel has begun to make up for its shortcomings and has begun to vaccinate teenagers on a large scale. On June 24, 11000 people were vaccinated, of which nearly 8000 were children aged 12-15 (the first vaccination).

我们继续听取国内专家的解读。

We continue to listen to the interpretation of domestic experts.

根据英国公共卫生局公布的研究数据，在两次完全注射后，辉瑞公司疫苗对"delta"菌株的有效性为87.9%，而对先前流行的"alpha"菌株的有效性为93.4%[1]。

According to the research data released by the public health bureau of England, after two full injections, the effectiveness of Pfizer vaccine against the "delta" strain was 87.9%, while the effectiveness against the previously prevalent "alpha" strain was 93.4% [1].

很明显，delta菌株削弱了辉瑞疫苗的保护作用。

Obviously, the delta strain weakened the protection of Pfizer vaccine.

此外，关于辉瑞疫苗在这一时期的副作用也有很多报道。根据美国疾控中心的报告，截至2021年1月18日，辉瑞公司的疫苗报告死亡113人，而另一个欧美国家接受的莫德纳疫苗较多，报告死亡83人。

In addition, there are many reports about the side effects of Pfizer vaccine during this period. According to the CDC report, as of January 18, 2021, Pfizer vaccine reported 113 deaths, while another European and American countries received more modna vaccine, reported 83 deaths.

尽管美国的CDC被初步认为是巧合事件，但辉瑞疫苗的安全性显然需要进一步观察[2]。

Although CDC in the United States is tentatively regarded as a coincidence event, the safety of Pfizer vaccine obviously needs further observation [2].

今年4月至5月，3人进入成都后被确认感染"三角洲"病毒。其中2人全部接种灭活疫苗（分别由北京生物和科兴中卫生产），另1人未接种。

From April to May this year, three people were confirmed to be infected with "delta" virus after entering Chengdu. Two of them were completely vaccinated with inactivated vaccine (produced by Beijing biology and Kexing Zhongwei respectively), and the other one was not vaccinated.

结果如下

The results are as follows

1.2名接种者中，1日和4日分别诊断为IgM和IgG抗体。未接种疫苗的人在第7天出现IgG抗体，抗体数量很少，而IgM抗体根本没有出现。

1. of the 2 vaccinated people were diagnosed with IgM and IgG antibodies at the first and fourth days respectively. The person who had not been vaccinated developed IgG antibodies on the 7th day, and the number of antibodies was small, while IgM antibodies did not appear at all.

2.两名接种者的病毒载量较低（即传染性较弱），解毒时间较短。

2. The two vaccinated people had lower viral load (i.e. weaker infectivity) and shorter detoxification time.

3.2例接种疫苗者住院时间分别为21天和25天，未接种疫苗者住院时间为36天。

3. The length of hospital stay of 2 vaccinated patients was 21 days and 25 days respectively, while that of the non vaccinated patients was 36 days.

总之，新型冠状病毒疫苗对Delta是有效的，可以改善感染者的状况。

In conclusion, the new coronal vaccine is effective for Delta and can improve the condition of infected people.

例如，在深圳机场最近爆发的疫情中，虽然一些工作人员感染了病毒，但87名密切接触者中没有报告感染病例。由此可见，集体免疫具有良好的防护效果。

For example, in the recent outbreak at Shenzhen airport, although some staff members were infected with the virus, no infection cases have been reported among 87 close contacts. This shows that the collective vaccination has a good protective effect.

2.继续采取强有力的控制和检疫措施。

2. Strong control and quarantine measures should be continued.

3.我们也希望尽快完成国产疫苗在儿童中的临床试验，让儿童在保证安全的前提下接种疫苗。

3. We also hope that the clinical trial of domestic vaccine in children can be completed as soon as possible, so that children can be vaccinated on the premise of ensuring safety.

特别作者：

Special author:

黄素在中东的专著作者

Huang Su | special author in the Middle East

姜永元

Jiang Yongyuan

审稿人：中国疾控中心病毒性疾病预防控制研究所助理研究员、免疫学博士卢学新

Reviewer: Lu Xuexin, assistant researcher and doctor of immunology, Institute of viral disease prevention and control, CDC

参考

reference

[1] Bernal JL，Andrews N，Gower C，等。针对B.1.617.2变体的COVID-19疫苗的有效性。医学十四。2020年。21257658v1。

[1]Bernal JL, Andrews N, Gower C, et al. Effectiveness of COVID-19 vaccines against the B.1.617.2 variant. medRxiv. 2020. 21257658v1.

https://www.medrxiv.org/content/10.1101/2021.05.22.21257658v1

https://www.medrxiv.org/content/10.1101/2021.05.22.21257658v1

[2] COVID-19疫苗安全更新

[2]COVID-19 vaccine safety update

https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2021-01/06-COVID-Shimabukuro.pdf

https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2021-01/06-COVID-Shimabukuro.pdf

[3] 陈恒，毛奕，段振华，等。3例有无疫苗接种的COVID-19变异三角洲病例——四川省成都市，2004年4月�中国医学会，2021年[J]。中国疾控中心周刊，2021，3（25）：544-546.doi:10.46234/ccdcw2021.137

[3]Heng Chen, Yi Mao, Zhenhua Duan, et al.Three Cases of COVID-19 Variant Delta With and Without Vaccination ― Chengdu City, Sichuan Province, April�CMay, 2021[J]. China CDC Weekly, 2021, 3(25): 544-546. doi: 10.46234/ccdcw2021.137

Link：https://new.qq.com/omn/20210630/20210630A01K1800.html

update time：2021-06-30 18:57:19